Home Tools
Log in
Cart

Search Result

Search Results for " muscarinic acetylcholine receptor m1 "

Targets

17

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T15942 MK-7622 M1 receptor modulator AChR
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
T7002 Trihexyphenidyl hydrochloride Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride AChR
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
T8219 VU0238441 AChR
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
T1049 Oxybutynin chloride Oxybutynin hydrochloride,Oxybutynin HCl Potassium Channel , AChR
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
T1475 Fesoterodine fumarate Toviaz,SPM 907 AChR
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo...
T27961 LY593093 LY 593093,LY-593093
LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.
T24469 MIPS1455 MIPS-1455,MIPS 1455
MIPS1455 is a photoactivatable allosteric M1 muscarinic acetylcholine receptor ligand.
T16758 Rispenzepine Others
Rispenzepine is a novel antagonist of muscarinic acetylcholine receptors (mAChRs), selectively targeting the M1 and M3 receptor subtypes, and can be used in the treatment of immune system disorders, infections, and respi...
T17245 VU0467485 AZ13713945 Others
VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respec...
T60728 M1 ligand 1
M1 ligand 1 (compound 3b-b) is a N-desmethyl congener of arecoline derivative that is a muscarinic acetylcholine receptor M1 ligand. M1 ligand 1 is able to be used as PET (positron emission tomography) radiotracer [1].
T23763 Atropine Oxide NSC 72861,NSC72861,NSC-72861
Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and ...
T61228 Pirenzepine
Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for inv...
T37728 Methoctramine (hydrate)
Methoctramine is a selective antagonist of M2 muscarinic acetylcholine receptors (IC50 = 6.1 nM in CHO-K1 cell membranes).[1] It is selective for M2 over M1, M3, M4, and M5 receptors (IC50s = 92, 770, 260, and 217 nM, re...
T69232 Atropine Oxide Hydrochloride
Atropine Oxide is a derivative of Atropine. Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surger...
T60577 Cycrimine
Cycrimine is an orally active antagonist of the muscarinic cholinergic receptor (mAChR) M1 that reduces the level of acetylcholine in the Parkinson's model. Cycrimine exhibits antispasmodic activity that can be used in b...
T38895 Zanapezil free base TAK-147 free base,Zanapezil free base
Zanapezil (TAK-147) is a powerful and selective inhibitor of acetylcholine esterase (AChE). It demonstrates significant and reversible inhibition of AChE activity in rat cerebral cortex homogenates (IC50 = 51.2 nM). Furt...
T36241 Arecaidine propargyl ester (hydrobromide)
Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0...
Cat No. Product Name Synonyms Targets
TN1653 Fustin ERK , Beta Amyloid , AChR
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03338 CHRM1 Protein, Rat, Recombinant (His) Rat E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TMPH-01714 CHRM1 Protein, Human, Recombinant (His) Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TargetMol